What's the difference between Ozempic and Wegovy?
Both contain semaglutide, both come as injections, and both are often mentioned in the same breath. But they are not the same. Here's what you need to know.
They contain the same active ingredient
Both Ozempic and Wegovy contain semaglutide — a GLP-1 receptor agonist that mimics a hormone involved in appetite regulation. They work the same way: slowing digestion, reducing hunger signals, and helping you feel full for longer.
But they're licensed for different purposes
Ozempic is licensed specifically for the management of type 2 diabetes. Its approved doses go up to 1 mg per week. It was not originally designed as a weight loss medication, though weight loss is a known side effect.
Wegovy is licensed specifically for weight management in adults with obesity. It uses higher doses — up to 2.4 mg per week — and clinical trials were conducted specifically with weight loss as the primary outcome. The results were more significant than those seen with Ozempic at its licensed dose.
What about Mounjaro?
Mounjaro (tirzepatide) is a different medication — it targets two hormones (GLP-1 and GIP) rather than one. Clinical trials have shown it produces greater average weight loss than semaglutide alone. It is now available on the NHS via specialist services for eligible patients.
Which one can I get on the NHS?
If you have type 2 diabetes, your GP may prescribe Ozempic (or similar semaglutide products) if you meet NHS criteria for diabetic management.
If you're seeking medication for weight loss without diabetes, your GP cannot prescribe Ozempic or Wegovy directly. The NHS pathway routes non-diabetic patients through specialist services like Oviva, where Wegovy may be prescribed as part of a structured programme.
Why do people ask for Ozempic for weight loss?
Media coverage often refers to Ozempic as a weight loss drug — partly because it became well known before Wegovy was widely available, and partly because some private clinics have been prescribing it off-label for weight management. This has caused supply shortages that have affected patients who rely on it for diabetes treatment.
If you're specifically seeking weight loss support, Wegovy or Mounjaro (via the NHS pathway) are the appropriate medications to discuss.
Want to explore your options?
Register with Abbamoor and book with our Clinical Pharmacist to find out whether you qualify for weight loss medication via the NHS.